Skin Functions and Mechanisms


The search for further knowledge on skin functions and mechanisms is at the core of many biomedical and biopharmaceutical research programs today. The extension and complexity of the skin justifies its multiple roles, affecting all physiological processes, far beyond its “barrier” characteristics. More research on skin physiology is needed to better understand various disease mechanisms, and these need not be confined to the skin itself. Skin is also a target for new molecules, supplements, materials and even instruments, with the potential to impact the whole body. Because of its accessibility and relative dimension, it is also a model to study several other body functions, including occupational impacts and adaptation to extreme (including non-terrestrial) conditions.

This holistic vision of human skin explains why skin functions and mechanisms are no longer exclusive subjects of dermatology, but rather a broad knowledge nucleus, attracting researchers from all areas. Whether coming from physiology and pathophysiology, from pharmacology, toxicology, chemistry and pharmaceutical science, from dermatology, cosmetic medicine or plastic surgery - you will be welcomed to contribute with your best research to our “Skin Functions and Mechanisms” research topic, to be housed in Frontiers in Physiology, actively linking scientists, clinical researchers and technicians sharing this common interest within human physiology.

This Journal of Clinical & Experimental Dermatology Research aims to deepen insight into the multiple skin characteristics in health and disease, opening a stage for innovation regarding new physiological principles or mechanisms. We welcome submission of research at the molecular, sub-cellular, cellular, organ, and organism level, including system and integrative physiology, and clinical proof-of-concept and/or translational studies.

Submissions to this Research Topic can be any of the article types (e.g., Original Research, methods, hypothesis & theory, opinions, Case reports, Reviews, etc.). Your contribution to our global scientific community can enhance this knowledge confluence and support an improved understanding of “Skin Functions and Mechanisms”.

A standard EDITORIAL TRACKING SYSTEM is utilized for manuscript submission, review, editorial processing and tracking which can be securely accessed by the authors, reviewers and editors for monitoring and tracking the article processing. Manuscripts can be uploaded online at Editorial Tracking System ( or forwarded to the Editorial Office at

Media Contact:

Kathy Andrews
Journal Manager
Journal of Clinical & Experimental Dermatology Research